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Isotec/Sigma Aldrich Nitric Oxide Explosion
FINAL REPORT: Isotec Case Study
Location: Miami Township, OH
Incident Occurred On: 09/21/2003
Final Report Released On: 08/24/2004
Incident Type: Chemical Manufacturing - Fire and Explosion
Company Name: Isotec

investigation information

Incident Description
On September 21, 2003, a violent explosion destroyed an underground distillation tower at the Isotec chemical manufacturing plant in Miami Township, Ohio, injuring one worker. The explosion ruptured a carbon monoxide gas pipe and led to a precautionary evacuation of about 2000 residents. The Isotec facility manufactures rare forms of oxygen and nitrogen, known as stable isotopes, which are used in research and medicine.
Investigation Status
CSB issued a case study report on this accident on August 24, 2004.



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CSB Issues Case Study on September 2003 Explosion at Isotec Facility in Miami Township, OH
Miami Township, OH, Aug. 24, 2004 - The U.S. Chemical Safety and Hazard Investigation Board (CSB) today issued a Case Study examining the causes of a Sept. 21, 2003 nitric oxide leak and explosion which occurred at a high-technology biochemical products plant in Miami Township, Ohio, near Dayton.
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(Washington, DC - September 29, 2003) Investigators from the U.S. Chemical Safety Board (CSB) are returning today to the site of last week's violent explosion at the Isotec chemical manufacturing plant in Miamisburg, Ohio, southwest of Dayton. The explosion ruptured a carbon monoxide pipe and ignited the gas, prompting a precautionary evacuation that affected about 2000 residents within a mile of the plant. CSB lead investigator John Vorderbrueggen and Board member John Bresland were en route back to the site and were expected to meet with concerned citizens today. The effectiveness of the emergency response and the evacuation order are important issues in the case, investigators say.
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